Fit a mixture of Gaussian distributions to log fold change

The standard deviation parameters are modeled either by linear or quadratic functions of log mean count and the mean parameter is modeled by linear functions of log mean count

Usage

logfoldchange_fit(
  logmean,
  logfoldchange,
  ncore = 2,
  max_sd_ord = 2,
  max_np = 5,
  minval = -5,
  maxval = 5,
  itermax = 100,
  NP = 800,
  seed = 100
)

Arguments

logmean

vector of log mean abundance

logfoldchange

vector of log fold change

ncore

number of cores to use

max_sd_ord

the maximum order of polynomial function to fit to standard deviation parameter. This must be either 1 (linear) or 2(quadratic)

max_np

maximum number of Gaussian components to check for

minval

minimum value for DEoptim search

maxval

maximum value for DEoptim search

itermax

maximum number of iterations

NP

the number of population members for DEoptim

seed

seed value

Value

A list.

   par is a vector of the estimates of the mixture proportion,
   the mean and standard deviation parameters,

   np is the number of gaussian components fitted

   sd_ord is the order for the function for the standard deviation

   aic is the aic of the best fit

Examples

# \donttest{
logmean        =  rnorm(100)
logfoldchange  =  rnorm(100)
logfoldchange_fit(logmean,logfoldchange)
#> Iteration: 1 bestvalit: 194.523582 bestmemit:    2.161104    0.387201   -0.848797    1.125176   -0.657651    0.200676    0.933742   -0.215245    0.159564
#> Iteration: 2 bestvalit: 194.523582 bestmemit:    2.161104    0.387201   -0.848797    1.125176   -0.657651    0.200676    0.933742   -0.215245    0.159564
#> Iteration: 3 bestvalit: 194.523582 bestmemit:    2.161104    0.387201   -0.848797    1.125176   -0.657651    0.200676    0.933742   -0.215245    0.159564
#> Iteration: 4 bestvalit: 194.523582 bestmemit:    2.161104    0.387201   -0.848797    1.125176   -0.657651    0.200676    0.933742   -0.215245    0.159564
#> Iteration: 5 bestvalit: 161.516985 bestmemit:    3.379229    2.470622    0.109671   -0.359803   -0.254248   -4.739450   -0.167364   -1.994900   -0.275809
#> Iteration: 6 bestvalit: 161.516985 bestmemit:    3.379229    2.470622    0.109671   -0.359803   -0.254248   -4.739450   -0.167364   -1.994900   -0.275809
#> Iteration: 7 bestvalit: 160.871458 bestmemit:    3.379229    2.470622    0.109671    2.245280   -0.254248   -4.739450   -0.167364   -1.994900   -0.275809
#> Iteration: 8 bestvalit: 160.871458 bestmemit:    3.379229    2.470622    0.109671    2.245280   -0.254248   -4.739450   -0.167364   -1.994900   -0.275809
#> Iteration: 9 bestvalit: 160.871458 bestmemit:    3.379229    2.470622    0.109671    2.245280   -0.254248   -4.739450   -0.167364   -1.994900   -0.275809
#> Iteration: 10 bestvalit: 160.871458 bestmemit:    3.379229    2.470622    0.109671    2.245280   -0.254248   -4.739450   -0.167364   -1.994900   -0.275809
#> Iteration: 11 bestvalit: 160.871458 bestmemit:    3.379229    2.470622    0.109671    2.245280   -0.254248   -4.739450   -0.167364   -1.994900   -0.275809
#> Iteration: 12 bestvalit: 160.806566 bestmemit:    1.493881    1.410879   -0.396196    2.540963    0.414014   -0.518834   -0.270506   -0.091625   -0.181885
#> Iteration: 13 bestvalit: 160.522551 bestmemit:    3.379229    2.470622    0.109671    2.245280   -0.254248   -0.900757   -0.167364   -1.994900   -0.275809
#> Iteration: 14 bestvalit: 160.522551 bestmemit:    3.379229    2.470622    0.109671    2.245280   -0.254248   -0.900757   -0.167364   -1.994900   -0.275809
#> Iteration: 15 bestvalit: 157.905888 bestmemit:    1.493881    1.410879   -0.396196    2.540963    0.414014   -2.940575   -0.270506   -0.091625   -0.181885
#> Iteration: 16 bestvalit: 157.905888 bestmemit:    1.493881    1.410879   -0.396196    2.540963    0.414014   -2.940575   -0.270506   -0.091625   -0.181885
#> Iteration: 17 bestvalit: 157.905888 bestmemit:    1.493881    1.410879   -0.396196    2.540963    0.414014   -2.940575   -0.270506   -0.091625   -0.181885
#> Iteration: 18 bestvalit: 153.620397 bestmemit:    4.830563    3.256635   -0.473879    3.839952    0.106201   -4.005095   -0.187958    0.589659   -0.063429
#> Iteration: 19 bestvalit: 153.620397 bestmemit:    4.830563    3.256635   -0.473879    3.839952    0.106201   -4.005095   -0.187958    0.589659   -0.063429
#> Iteration: 20 bestvalit: 153.110342 bestmemit:    4.830563   -1.194870   -0.473879    3.839952    0.106201   -4.005095   -0.187958    0.589659   -0.063429
#> Iteration: 21 bestvalit: 153.110342 bestmemit:    4.830563   -1.194870   -0.473879    3.839952    0.106201   -4.005095   -0.187958    0.589659   -0.063429
#> Iteration: 22 bestvalit: 146.694905 bestmemit:    4.935283    0.213487   -0.015882    1.276293    0.472531    0.959364    0.160179   -3.758759   -0.279162
#> Iteration: 23 bestvalit: 146.694905 bestmemit:    4.935283    0.213487   -0.015882    1.276293    0.472531    0.959364    0.160179   -3.758759   -0.279162
#> Iteration: 24 bestvalit: 146.694905 bestmemit:    4.935283    0.213487   -0.015882    1.276293    0.472531    0.959364    0.160179   -3.758759   -0.279162
#> Iteration: 25 bestvalit: 146.694905 bestmemit:    4.935283    0.213487   -0.015882    1.276293    0.472531    0.959364    0.160179   -3.758759   -0.279162
#> Iteration: 26 bestvalit: 146.694905 bestmemit:    4.935283    0.213487   -0.015882    1.276293    0.472531    0.959364    0.160179   -3.758759   -0.279162
#> Iteration: 27 bestvalit: 146.694905 bestmemit:    4.935283    0.213487   -0.015882    1.276293    0.472531    0.959364    0.160179   -3.758759   -0.279162
#> Iteration: 28 bestvalit: 146.694905 bestmemit:    4.935283    0.213487   -0.015882    1.276293    0.472531    0.959364    0.160179   -3.758759   -0.279162
#> Iteration: 29 bestvalit: 146.694905 bestmemit:    4.935283    0.213487   -0.015882    1.276293    0.472531    0.959364    0.160179   -3.758759   -0.279162
#> Iteration: 30 bestvalit: 146.694905 bestmemit:    4.935283    0.213487   -0.015882    1.276293    0.472531    0.959364    0.160179   -3.758759   -0.279162
#> Iteration: 31 bestvalit: 146.694905 bestmemit:    4.935283    0.213487   -0.015882    1.276293    0.472531    0.959364    0.160179   -3.758759   -0.279162
#> Iteration: 32 bestvalit: 146.694905 bestmemit:    4.935283    0.213487   -0.015882    1.276293    0.472531    0.959364    0.160179   -3.758759   -0.279162
#> Iteration: 33 bestvalit: 146.694905 bestmemit:    4.935283    0.213487   -0.015882    1.276293    0.472531    0.959364    0.160179   -3.758759   -0.279162
#> Iteration: 34 bestvalit: 146.694905 bestmemit:    4.935283    0.213487   -0.015882    1.276293    0.472531    0.959364    0.160179   -3.758759   -0.279162
#> Iteration: 35 bestvalit: 146.332149 bestmemit:    3.433812    1.792112    0.042006    0.485478    0.465713    1.290608    0.170908    1.360195   -0.122976
#> Iteration: 36 bestvalit: 146.332149 bestmemit:    3.433812    1.792112    0.042006    0.485478    0.465713    1.290608    0.170908    1.360195   -0.122976
#> Iteration: 37 bestvalit: 142.979049 bestmemit:    4.218914    0.193411   -0.267290   -0.538363    0.065314    3.043889   -0.019048   -1.130013    0.100194
#> Iteration: 38 bestvalit: 142.979049 bestmemit:    4.218914    0.193411   -0.267290   -0.538363    0.065314    3.043889   -0.019048   -1.130013    0.100194
#> Iteration: 39 bestvalit: 139.136605 bestmemit:    4.763463    0.587099    0.062146   -1.433413    0.208536   -1.027734   -0.125828    2.655954    0.004535
#> Iteration: 40 bestvalit: 139.136605 bestmemit:    4.763463    0.587099    0.062146   -1.433413    0.208536   -1.027734   -0.125828    2.655954    0.004535
#> Iteration: 41 bestvalit: 139.136605 bestmemit:    4.763463    0.587099    0.062146   -1.433413    0.208536   -1.027734   -0.125828    2.655954    0.004535
#> Iteration: 42 bestvalit: 138.784441 bestmemit:    4.763463    3.027158   -0.051097    2.457182    0.208536   -1.027734   -0.125828    2.655954    0.004535
#> Iteration: 43 bestvalit: 138.784441 bestmemit:    4.763463    3.027158   -0.051097    2.457182    0.208536   -1.027734   -0.125828    2.655954    0.004535
#> Iteration: 44 bestvalit: 138.618718 bestmemit:    4.763463    1.871474   -0.051097    2.457182    0.208536   -1.027734   -0.125828    2.655954    0.004535
#> Iteration: 45 bestvalit: 138.618718 bestmemit:    4.763463    1.871474   -0.051097    2.457182    0.208536   -1.027734   -0.125828    2.655954    0.004535
#> Iteration: 46 bestvalit: 138.618718 bestmemit:    4.763463    1.871474   -0.051097    2.457182    0.208536   -1.027734   -0.125828    2.655954    0.004535
#> Iteration: 47 bestvalit: 138.618718 bestmemit:    4.763463    1.871474   -0.051097    2.457182    0.208536   -1.027734   -0.125828    2.655954    0.004535
#> Iteration: 48 bestvalit: 138.618718 bestmemit:    4.763463    1.871474   -0.051097    2.457182    0.208536   -1.027734   -0.125828    2.655954    0.004535
#> Iteration: 49 bestvalit: 138.618718 bestmemit:    4.763463    1.871474   -0.051097    2.457182    0.208536   -1.027734   -0.125828    2.655954    0.004535
#> Iteration: 50 bestvalit: 138.618718 bestmemit:    4.763463    1.871474   -0.051097    2.457182    0.208536   -1.027734   -0.125828    2.655954    0.004535
#> Iteration: 51 bestvalit: 138.618718 bestmemit:    4.763463    1.871474   -0.051097    2.457182    0.208536   -1.027734   -0.125828    2.655954    0.004535
#> Iteration: 52 bestvalit: 138.618718 bestmemit:    4.763463    1.871474   -0.051097    2.457182    0.208536   -1.027734   -0.125828    2.655954    0.004535
#> Iteration: 53 bestvalit: 138.362208 bestmemit:    4.763463    1.871474   -0.051097    0.526554    0.208536   -1.027734   -0.125828    2.655954    0.004535
#> Iteration: 54 bestvalit: 138.362208 bestmemit:    4.763463    1.871474   -0.051097    0.526554    0.208536   -1.027734   -0.125828    2.655954    0.004535
#> Iteration: 55 bestvalit: 138.362208 bestmemit:    4.763463    1.871474   -0.051097    0.526554    0.208536   -1.027734   -0.125828    2.655954    0.004535
#> Iteration: 56 bestvalit: 137.533712 bestmemit:    4.518542   -0.247764   -0.179988   -0.115626    0.000053   -1.750924    0.008267   -2.567164   -0.034539
#> Iteration: 57 bestvalit: 135.863999 bestmemit:    2.259217    0.007053   -0.151067   -0.476349    0.148975   -0.757271   -0.041740    1.105205   -0.067334
#> Iteration: 58 bestvalit: 135.863999 bestmemit:    2.259217    0.007053   -0.151067   -0.476349    0.148975   -0.757271   -0.041740    1.105205   -0.067334
#> Iteration: 59 bestvalit: 135.863999 bestmemit:    2.259217    0.007053   -0.151067   -0.476349    0.148975   -0.757271   -0.041740    1.105205   -0.067334
#> Iteration: 60 bestvalit: 135.863999 bestmemit:    2.259217    0.007053   -0.151067   -0.476349    0.148975   -0.757271   -0.041740    1.105205   -0.067334
#> Iteration: 61 bestvalit: 135.863999 bestmemit:    2.259217    0.007053   -0.151067   -0.476349    0.148975   -0.757271   -0.041740    1.105205   -0.067334
#> Iteration: 62 bestvalit: 135.863999 bestmemit:    2.259217    0.007053   -0.151067   -0.476349    0.148975   -0.757271   -0.041740    1.105205   -0.067334
#> Iteration: 63 bestvalit: 132.226791 bestmemit:    2.259217    0.007053   -0.151067   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 64 bestvalit: 132.226791 bestmemit:    2.259217    0.007053   -0.151067   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 65 bestvalit: 132.226791 bestmemit:    2.259217    0.007053   -0.151067   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 66 bestvalit: 132.226791 bestmemit:    2.259217    0.007053   -0.151067   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 67 bestvalit: 132.226791 bestmemit:    2.259217    0.007053   -0.151067   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 68 bestvalit: 132.226791 bestmemit:    2.259217    0.007053   -0.151067   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 69 bestvalit: 132.226791 bestmemit:    2.259217    0.007053   -0.151067   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 70 bestvalit: 132.226791 bestmemit:    2.259217    0.007053   -0.151067   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 71 bestvalit: 132.226791 bestmemit:    2.259217    0.007053   -0.151067   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 72 bestvalit: 132.226791 bestmemit:    2.259217    0.007053   -0.151067   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 73 bestvalit: 132.226791 bestmemit:    2.259217    0.007053   -0.151067   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 74 bestvalit: 132.226791 bestmemit:    2.259217    0.007053   -0.151067   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 75 bestvalit: 132.226791 bestmemit:    2.259217    0.007053   -0.151067   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 76 bestvalit: 131.704424 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 77 bestvalit: 131.704424 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 78 bestvalit: 131.704424 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 79 bestvalit: 131.704424 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 80 bestvalit: 131.704424 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 81 bestvalit: 131.704424 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 82 bestvalit: 131.704424 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 83 bestvalit: 131.704424 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 84 bestvalit: 131.704424 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 85 bestvalit: 131.704424 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.148975   -2.968439   -0.041740    1.105205   -0.067334
#> Iteration: 86 bestvalit: 131.150296 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.148975   -2.968439   -0.041740    1.681655   -0.067334
#> Iteration: 87 bestvalit: 131.100244 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.161181   -2.968439   -0.041740    1.681655   -0.067334
#> Iteration: 88 bestvalit: 131.100244 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.161181   -2.968439   -0.041740    1.681655   -0.067334
#> Iteration: 89 bestvalit: 131.100244 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.161181   -2.968439   -0.041740    1.681655   -0.067334
#> Iteration: 90 bestvalit: 131.100244 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.161181   -2.968439   -0.041740    1.681655   -0.067334
#> Iteration: 91 bestvalit: 131.100244 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.161181   -2.968439   -0.041740    1.681655   -0.067334
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#> Iteration: 93 bestvalit: 131.100244 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.161181   -2.968439   -0.041740    1.681655   -0.067334
#> Iteration: 94 bestvalit: 131.100244 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.161181   -2.968439   -0.041740    1.681655   -0.067334
#> Iteration: 95 bestvalit: 131.100244 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.161181   -2.968439   -0.041740    1.681655   -0.067334
#> Iteration: 96 bestvalit: 131.100244 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.161181   -2.968439   -0.041740    1.681655   -0.067334
#> Iteration: 97 bestvalit: 131.100244 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.161181   -2.968439   -0.041740    1.681655   -0.067334
#> Iteration: 98 bestvalit: 131.100244 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.161181   -2.968439   -0.041740    1.681655   -0.067334
#> Iteration: 99 bestvalit: 131.100244 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.161181   -2.968439   -0.041740    1.681655   -0.067334
#> Iteration: 100 bestvalit: 131.100244 bestmemit:    2.259217    0.007053   -0.076362   -0.476349    0.161181   -2.968439   -0.041740    1.681655   -0.067334
#> Iteration: 1 bestvalit: 197.595230 bestmemit:    0.984209    3.529700   -2.710079    3.494636   -0.044943   -2.626876   -0.741566   -0.122650    2.526074   -2.984686    0.645590   -2.906226    1.007665    0.623440
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#> Iteration: 10 bestvalit: 171.941648 bestmemit:    1.478718   -2.761613    2.870413    1.582133   -2.205654   -1.249272   -4.336798   -0.081932    1.016296   -1.708741    2.615431    1.506140    0.377536   -0.792652   -3.800927    0.400259   -2.924928    0.219999    1.278350    0.853534   -1.044004    0.874628   -0.506834   -1.338563
#> Iteration: 11 bestvalit: 170.392123 bestmemit:   -1.168177   -3.551007    2.924372   -4.368183   -0.036456   -4.204739   -1.350583    0.199979    3.663181    1.997357    3.475567    1.164813    0.779627   -4.827656    0.824111   -3.496753    0.343466    0.412987   -2.947100   -1.233483    3.034574    0.148872    0.180034    0.534766
#> Iteration: 12 bestvalit: 170.392123 bestmemit:   -1.168177   -3.551007    2.924372   -4.368183   -0.036456   -4.204739   -1.350583    0.199979    3.663181    1.997357    3.475567    1.164813    0.779627   -4.827656    0.824111   -3.496753    0.343466    0.412987   -2.947100   -1.233483    3.034574    0.148872    0.180034    0.534766
#> Iteration: 13 bestvalit: 167.479741 bestmemit:   -3.461483   -0.665088    4.079138   -4.801038   -1.238507    1.666585    4.271660    0.359337   -0.615762   -0.723903    2.002617    4.243940   -0.075526   -2.388837   -1.661290    3.539492   -2.867931    0.403871   -3.003510    3.673619   -4.805368    4.251944   -0.553040    2.644452
#> Iteration: 14 bestvalit: 164.111269 bestmemit:   -1.174885    0.220971    2.489073    0.154876   -2.895686    1.946939    1.546480    0.249425   -3.123179   -3.177965    3.235352   -3.002377    0.108353   -1.317182   -1.969711   -0.799838   -1.886580    0.222502    1.070090    0.959769   -2.779140    2.745701    0.042402   -1.238847
#> Iteration: 15 bestvalit: 164.111269 bestmemit:   -1.174885    0.220971    2.489073    0.154876   -2.895686    1.946939    1.546480    0.249425   -3.123179   -3.177965    3.235352   -3.002377    0.108353   -1.317182   -1.969711   -0.799838   -1.886580    0.222502    1.070090    0.959769   -2.779140    2.745701    0.042402   -1.238847
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#> Iteration: 17 bestvalit: 163.468183 bestmemit:   -1.174885    0.220971    2.489073    0.154876   -2.895686    1.946939    1.546480    0.249425   -2.019570   -3.177965    3.235352   -3.002377    0.108353   -1.317182   -1.969711   -0.799838   -1.886580    0.222502    1.070090    0.959769   -2.779140    2.745701    0.042402   -1.238847
#> Iteration: 18 bestvalit: 163.442405 bestmemit:   -1.174885    0.220971    2.489073    0.154876   -2.895686    1.946939    1.546480    0.249425   -2.019570   -3.177965    3.235352   -3.002377    0.108353   -1.317182   -1.969711   -0.799838   -1.886580    0.222502    1.070090    0.959769   -2.779140    2.646372    0.042402   -1.238847
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#> Iteration: 20 bestvalit: 163.442405 bestmemit:   -1.174885    0.220971    2.489073    0.154876   -2.895686    1.946939    1.546480    0.249425   -2.019570   -3.177965    3.235352   -3.002377    0.108353   -1.317182   -1.969711   -0.799838   -1.886580    0.222502    1.070090    0.959769   -2.779140    2.646372    0.042402   -1.238847
#> Iteration: 21 bestvalit: 160.237711 bestmemit:   -2.419392    4.328853    0.146443    0.109799   -2.742395    4.890954    0.598303   -1.514136   -4.090563   -4.934560    3.368446    0.481423    0.504811   -4.397308   -3.693575   -3.186756    0.074742   -1.382996   -0.134084   -1.253310    2.240958    0.166748   -2.815809   -0.265901
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#> Iteration: 27 bestvalit: 160.212474 bestmemit:   -2.419392    4.328853    0.146443    0.109799   -2.742395    4.890954    0.598303   -1.514136   -4.090563   -4.934560    3.368446    0.481423    0.504811   -4.397308   -3.081153   -3.186756    0.074742   -1.382996   -0.134084   -1.253310    2.240958    0.166748   -2.815809   -0.265901
#> Iteration: 28 bestvalit: 159.872649 bestmemit:    3.931290   -2.567012    1.682438   -2.292929    3.906795   -0.116900    3.888508    1.736869    0.418493    3.052266   -0.029982    3.982801   -2.373207   -0.722420    4.571140    0.370153   -4.264296   -0.799061   -2.769500   -0.460452    0.179761   -1.502966   -2.051784   -3.366239
#> Iteration: 29 bestvalit: 159.872649 bestmemit:    3.931290   -2.567012    1.682438   -2.292929    3.906795   -0.116900    3.888508    1.736869    0.418493    3.052266   -0.029982    3.982801   -2.373207   -0.722420    4.571140    0.370153   -4.264296   -0.799061   -2.769500   -0.460452    0.179761   -1.502966   -2.051784   -3.366239
#> Iteration: 30 bestvalit: 149.717569 bestmemit:   -1.174885   -1.589690    3.174013   -2.485682    1.016989    1.946939    1.546480    0.249425   -2.019570   -3.177965    3.235352   -3.002377    0.108353   -1.317182   -1.969711   -0.799838   -1.886580    0.222502    1.070090    0.959769   -2.779140    2.646372    0.042402   -0.077530
#> Iteration: 31 bestvalit: 148.075462 bestmemit:   -1.174885   -1.589690    3.174013   -2.485682    1.016989    1.946939    1.546480    0.249425   -2.019570   -3.177965    3.235352   -3.002377    0.108353   -1.317182   -1.969711   -0.799838   -1.886580    0.222502    1.070090   -3.647282   -2.779140    2.646372    0.042402   -0.077530
#> Iteration: 32 bestvalit: 148.075462 bestmemit:   -1.174885   -1.589690    3.174013   -2.485682    1.016989    1.946939    1.546480    0.249425   -2.019570   -3.177965    3.235352   -3.002377    0.108353   -1.317182   -1.969711   -0.799838   -1.886580    0.222502    1.070090   -3.647282   -2.779140    2.646372    0.042402   -0.077530
#> Iteration: 33 bestvalit: 148.075462 bestmemit:   -1.174885   -1.589690    3.174013   -2.485682    1.016989    1.946939    1.546480    0.249425   -2.019570   -3.177965    3.235352   -3.002377    0.108353   -1.317182   -1.969711   -0.799838   -1.886580    0.222502    1.070090   -3.647282   -2.779140    2.646372    0.042402   -0.077530
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#> Iteration: 36 bestvalit: 148.042895 bestmemit:   -1.174885   -1.589690    3.174013   -2.485682    1.016989    1.946939    1.546480    0.249425   -2.019570   -3.177965    3.235352   -3.002377    0.108353   -1.317182   -1.969711   -0.799838   -1.886580    0.222502    0.657142   -3.647282   -2.779140    2.646372    0.042402   -0.077530
#> Iteration: 37 bestvalit: 147.946344 bestmemit:   -1.174885   -1.589690    4.203740   -0.707081   -0.511212    1.946939    1.546480    0.249425   -2.019570   -3.177965    3.235352   -3.002377    0.108353   -1.317182   -1.969711   -0.799838   -1.886580    0.222502    0.657142   -3.647282   -2.779140    2.646372    0.042402   -0.077530
#> Iteration: 38 bestvalit: 147.929363 bestmemit:   -1.174885   -1.589690    4.203740   -0.707081   -0.511212    1.946939    1.546480    0.249425   -2.019570   -3.177965    3.235352   -3.002377    0.108353   -1.317182   -1.969711   -3.486224   -1.886580    0.222502    0.657142   -3.647282   -2.779140    2.646372    0.042402   -0.077530
#> Iteration: 39 bestvalit: 141.076338 bestmemit:    4.270194   -1.314288   -4.634700   -2.921264   -1.650967   -0.157719    1.987542   -1.559765    3.620408    1.226122    0.149266    0.383574    0.166550    2.479908   -2.886434   -0.232121   -2.187026    1.871873    3.252853    0.279693   -0.121315   -1.124401   -0.587680    3.127703
#> Iteration: 40 bestvalit: 141.057112 bestmemit:    4.270194   -1.314288   -4.634700   -2.921264   -1.650967   -0.157719    1.987542   -1.559765    3.620408    1.226122    0.149266    1.386315    3.248734    2.479908   -2.886434   -0.232121   -2.187026    1.871873    3.252853    0.279693   -0.121315   -1.124401   -0.587680    3.127703
#> Iteration: 41 bestvalit: 139.740187 bestmemit:    4.270194   -1.314288   -4.634700   -2.921264   -1.650967   -0.157719    1.987542   -1.559765    3.620408    1.226122    0.149266    1.386315    3.248734    4.141559   -1.943318   -0.232121   -2.187026    1.871873    3.252853    0.279693   -0.121315   -1.124401   -0.587680    3.127703
#> Iteration: 42 bestvalit: 139.740187 bestmemit:    4.270194   -1.314288   -4.634700   -2.921264   -1.650967   -0.157719    1.987542   -1.559765    3.620408    1.226122    0.149266    1.386315    3.248734    4.141559   -1.943318   -0.232121   -2.187026    1.871873    3.252853    0.279693   -0.121315   -1.124401   -0.587680    3.127703
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#> Iteration: 80 bestvalit: 153.974816 bestmemit:   -4.773738    1.905382   -1.256042   -4.106892    0.054407   -1.453864   -0.240667   -2.062788    0.986591    2.505193    3.511434   -0.258139    4.438439   -3.974305    0.073761   -1.507285   -0.305200    0.831389    1.202533    4.142870    0.088852   -0.050219   -0.035567   -4.129491    3.181215   -0.007776    0.294941   -3.640541   -0.909994
#> Iteration: 81 bestvalit: 153.974816 bestmemit:   -4.773738    1.905382   -1.256042   -4.106892    0.054407   -1.453864   -0.240667   -2.062788    0.986591    2.505193    3.511434   -0.258139    4.438439   -3.974305    0.073761   -1.507285   -0.305200    0.831389    1.202533    4.142870    0.088852   -0.050219   -0.035567   -4.129491    3.181215   -0.007776    0.294941   -3.640541   -0.909994
#> Iteration: 82 bestvalit: 153.974816 bestmemit:   -4.773738    1.905382   -1.256042   -4.106892    0.054407   -1.453864   -0.240667   -2.062788    0.986591    2.505193    3.511434   -0.258139    4.438439   -3.974305    0.073761   -1.507285   -0.305200    0.831389    1.202533    4.142870    0.088852   -0.050219   -0.035567   -4.129491    3.181215   -0.007776    0.294941   -3.640541   -0.909994
#> Iteration: 83 bestvalit: 153.974816 bestmemit:   -4.773738    1.905382   -1.256042   -4.106892    0.054407   -1.453864   -0.240667   -2.062788    0.986591    2.505193    3.511434   -0.258139    4.438439   -3.974305    0.073761   -1.507285   -0.305200    0.831389    1.202533    4.142870    0.088852   -0.050219   -0.035567   -4.129491    3.181215   -0.007776    0.294941   -3.640541   -0.909994
#> Iteration: 84 bestvalit: 153.974816 bestmemit:   -4.773738    1.905382   -1.256042   -4.106892    0.054407   -1.453864   -0.240667   -2.062788    0.986591    2.505193    3.511434   -0.258139    4.438439   -3.974305    0.073761   -1.507285   -0.305200    0.831389    1.202533    4.142870    0.088852   -0.050219   -0.035567   -4.129491    3.181215   -0.007776    0.294941   -3.640541   -0.909994
#> Iteration: 85 bestvalit: 153.974816 bestmemit:   -4.773738    1.905382   -1.256042   -4.106892    0.054407   -1.453864   -0.240667   -2.062788    0.986591    2.505193    3.511434   -0.258139    4.438439   -3.974305    0.073761   -1.507285   -0.305200    0.831389    1.202533    4.142870    0.088852   -0.050219   -0.035567   -4.129491    3.181215   -0.007776    0.294941   -3.640541   -0.909994
#> Iteration: 86 bestvalit: 153.181776 bestmemit:   -4.773738    1.905382   -1.256042   -4.106892    0.054407   -1.453864    0.127224   -2.062788    0.986591    2.505193    3.511434   -0.258139    4.438439   -3.974305    0.073761   -1.507285   -0.305200    0.831389    1.202533    4.142870    0.088852   -0.050219   -0.035567   -4.129491    3.181215   -0.007776    0.294941   -3.640541   -0.909994
#> Iteration: 87 bestvalit: 153.181776 bestmemit:   -4.773738    1.905382   -1.256042   -4.106892    0.054407   -1.453864    0.127224   -2.062788    0.986591    2.505193    3.511434   -0.258139    4.438439   -3.974305    0.073761   -1.507285   -0.305200    0.831389    1.202533    4.142870    0.088852   -0.050219   -0.035567   -4.129491    3.181215   -0.007776    0.294941   -3.640541   -0.909994
#> Iteration: 88 bestvalit: 150.204713 bestmemit:   -4.780128    3.811502   -1.256042   -4.106892    0.054407   -1.453864    0.127224   -2.062788    0.986591    2.505193    3.511434   -0.258139    4.438439   -3.974305    0.073761   -1.507285   -0.305200    0.831389    1.202533    4.142870    0.088852   -0.050219   -0.035567   -4.129491    3.181215   -0.007776    0.294941   -3.640541   -0.909994
#> Iteration: 89 bestvalit: 150.204713 bestmemit:   -4.780128    3.811502   -1.256042   -4.106892    0.054407   -1.453864    0.127224   -2.062788    0.986591    2.505193    3.511434   -0.258139    4.438439   -3.974305    0.073761   -1.507285   -0.305200    0.831389    1.202533    4.142870    0.088852   -0.050219   -0.035567   -4.129491    3.181215   -0.007776    0.294941   -3.640541   -0.909994
#> Iteration: 90 bestvalit: 150.204713 bestmemit:   -4.780128    3.811502   -1.256042   -4.106892    0.054407   -1.453864    0.127224   -2.062788    0.986591    2.505193    3.511434   -0.258139    4.438439   -3.974305    0.073761   -1.507285   -0.305200    0.831389    1.202533    4.142870    0.088852   -0.050219   -0.035567   -4.129491    3.181215   -0.007776    0.294941   -3.640541   -0.909994
#> Iteration: 91 bestvalit: 150.204713 bestmemit:   -4.780128    3.811502   -1.256042   -4.106892    0.054407   -1.453864    0.127224   -2.062788    0.986591    2.505193    3.511434   -0.258139    4.438439   -3.974305    0.073761   -1.507285   -0.305200    0.831389    1.202533    4.142870    0.088852   -0.050219   -0.035567   -4.129491    3.181215   -0.007776    0.294941   -3.640541   -0.909994
#> Iteration: 92 bestvalit: 150.204713 bestmemit:   -4.780128    3.811502   -1.256042   -4.106892    0.054407   -1.453864    0.127224   -2.062788    0.986591    2.505193    3.511434   -0.258139    4.438439   -3.974305    0.073761   -1.507285   -0.305200    0.831389    1.202533    4.142870    0.088852   -0.050219   -0.035567   -4.129491    3.181215   -0.007776    0.294941   -3.640541   -0.909994
#> Iteration: 93 bestvalit: 150.204713 bestmemit:   -4.780128    3.811502   -1.256042   -4.106892    0.054407   -1.453864    0.127224   -2.062788    0.986591    2.505193    3.511434   -0.258139    4.438439   -3.974305    0.073761   -1.507285   -0.305200    0.831389    1.202533    4.142870    0.088852   -0.050219   -0.035567   -4.129491    3.181215   -0.007776    0.294941   -3.640541   -0.909994
#> Iteration: 94 bestvalit: 149.672232 bestmemit:   -4.780128    3.811502   -1.256042   -4.106892    0.054407   -1.453864    0.127224   -2.062788    0.986591    2.505193    3.511434   -0.258139    4.438439   -3.974305    0.073761   -1.507285   -0.305200    0.831389    1.202533    4.142870    0.088852   -0.050219   -0.035567   -4.129491    2.155177   -0.007776    0.294941   -3.640541   -0.909994
#> Iteration: 95 bestvalit: 149.672232 bestmemit:   -4.780128    3.811502   -1.256042   -4.106892    0.054407   -1.453864    0.127224   -2.062788    0.986591    2.505193    3.511434   -0.258139    4.438439   -3.974305    0.073761   -1.507285   -0.305200    0.831389    1.202533    4.142870    0.088852   -0.050219   -0.035567   -4.129491    2.155177   -0.007776    0.294941   -3.640541   -0.909994
#> Iteration: 96 bestvalit: 149.672232 bestmemit:   -4.780128    3.811502   -1.256042   -4.106892    0.054407   -1.453864    0.127224   -2.062788    0.986591    2.505193    3.511434   -0.258139    4.438439   -3.974305    0.073761   -1.507285   -0.305200    0.831389    1.202533    4.142870    0.088852   -0.050219   -0.035567   -4.129491    2.155177   -0.007776    0.294941   -3.640541   -0.909994
#> Iteration: 97 bestvalit: 149.606470 bestmemit:   -4.780128    3.811502   -1.256042   -4.106892    0.054407   -1.453864    0.127224   -2.062788    0.986591    2.512458    3.511434   -0.258139    4.438439   -3.974305    0.073761   -1.507285   -0.305200    0.831389    1.202533    4.142870    0.088852   -0.050219   -0.035567   -4.129491    2.155177   -0.007776    0.294941   -3.640541   -0.909994
#> Iteration: 98 bestvalit: 149.606470 bestmemit:   -4.780128    3.811502   -1.256042   -4.106892    0.054407   -1.453864    0.127224   -2.062788    0.986591    2.512458    3.511434   -0.258139    4.438439   -3.974305    0.073761   -1.507285   -0.305200    0.831389    1.202533    4.142870    0.088852   -0.050219   -0.035567   -4.129491    2.155177   -0.007776    0.294941   -3.640541   -0.909994
#> Iteration: 99 bestvalit: 149.545373 bestmemit:   -3.408812    3.811502   -1.256042   -4.106892    0.054407   -1.453864    0.127224   -2.062788    0.986591    2.512458    3.511434   -0.258139    4.438439   -3.974305    0.073761   -1.507285   -0.305200    0.831389    1.202533    4.142870    0.088852   -0.050219   -0.035567   -4.129491    2.155177   -0.007776    0.294941   -3.640541   -1.267451
#> Iteration: 100 bestvalit: 149.545373 bestmemit:   -3.408812    3.811502   -1.256042   -4.106892    0.054407   -1.453864    0.127224   -2.062788    0.986591    2.512458    3.511434   -0.258139    4.438439   -3.974305    0.073761   -1.507285   -0.305200    0.831389    1.202533    4.142870    0.088852   -0.050219   -0.035567   -4.129491    2.155177   -0.007776    0.294941   -3.640541   -1.267451
#> $par
#>  logitprob_1     mu_int_1     mu_int_2   mu_slope_1   mu_slope_2   logsd_.1_1 
#>  2.259217097  0.007053146 -0.076362153 -0.476349228  0.161181074 -2.968438892 
#>   logsd_.1_2   logsd_.L_1   logsd_.L_2 
#> -0.041740383  1.681654773 -0.067334095 
#> 
#> $np
#> [1] 2
#> 
#> $sd_ord
#> [1] 1
#> 
#> $aic
#> [1] 280.2005
#> 
# }